Vaccines against potential pathogens

Abstract

We proposed human intestine as the gate for the delivery of the therapeutic recombinant proteins expressed inside of the human body.  The normal intestinal microflora was used to express the selected genes of the pathogenic organism Yersinia pestis the causative agent for plug in humans and animals.  We have confirmed the production of the selected proteins by the PCR to their DNAs expressed in intestinal bifidobacteria chosen.  Now it is the role of the immunologists to find the antibodies for the recombinant proteins expressed inside of the volunteer’s organism. Key words: Expression of the recombinant proteins inside human’s body; Bifidobacterium breve; use of genome tailoring technology to express the recombinant proteins inside of the volunteer’s body.