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Sacroiliitis in patients with low backache with Normal Lumbosacral spine MRI
Sacroiliitis in patients with low backache with Normal Lumbosacral spine MRI
Dr. Bushra Mohsen Abdulla, Dr. Fatimah Hameed Khairullah
The detection and characterization of sacroiliac lesions on MR imaging has been well established, but its presence during evaluation of low backache cases has not been fully analyzed. Aim: determine the presence of sacroiliitis in cases with low back ache found to have a normal lumbosacral spine MRI and analyze its prevalence and radiological patterns Patients and Methods: A diagnostic study recruit 72 patients, they referred for lumbosacral spine MRI (1.5 Tesla) unit (16 channel coil) in Al- Sader- Medical City between March and August of the last year. Patients with abnormal LSS MRI were excluded .Information was taken from all patients about past medical and surgical history. Patients with normal LSS MRI were further evaluated for SIJ fast spin echo MRI applying the following study protocol: FSE coronal T1 WI & T2 WI STIR if abnormal finding seen then intravenous contrast gadolinium-DTPA about 0.1 mmol/ kg of body mass was injected and rescanned 10 minutes after injection to rule out the existing sacroiliitis or other SIJ abnormalities. Results: 72 patients with mean age of 33.2 ± 10.11 years ,male to female ratio was (1:2.483), a small but significant number of patients with sacroiliitis seen in patients with normal LSS MRI, there was no significant statistical differences between patients with normal finding and those with sacroiliitis. Three-fifth of the patients show narrowing of the joint space and one fifth show widening. The study revealed that all the patients had articular erosion and one fifth of the patients showed bone marrow edema. Conclusions: Sacroiliac joint lesions accounts small but significant number of lower backache patients. The enforcement of the diagnostic value and utility of adding a single fat suppressed sequence of the lumbo-sacral region in the coronal plane; adds marginally to the scan time but increases the yield of identifying incidental or manifest sacroiliac involvement in all cases referred for MRI for low backache.
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Clinical Outcome Of Corona Virus Disease-19 Patients In An Infectious Disease Center, Olodo, Ibadan, Oyo State, Nigeria
Clinical Outcome Of Corona Virus Disease-19 Patients In An Infectious Disease Center, Olodo, Ibadan, Oyo State, Nigeria
Oluwagbenga Alonge, Fowotade Adeol, Folasade Bamidele, Toyosi Omotosho, Moradeyo Aboluwoye,...
Introduction: Corona Virus Disease (COVID-19) is a severe respiratory infection caused by the newly emerged Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2). Globally, mortality from this disease is high and infection sequelae can result in long-term illness. COVID-19 is a new disease and the best way to manage patients remains uncertain, particularly in resource-limited settings. An evaluation of the clinical outcome of COVID-19 cases managed at the Infectious Disease Center (IDC), Olodo in Ibadan, Oyo State, Nigeria over a period of eighteen weeks was carried out. This center (IDC), Olodo was designated by the Oyo State COVID-19 Task Force to manage mild to severe cases of COVID-19 in Oyo state.
Materials and Methods: A treatment protocol designed by the Case Management Team of the Oyo State COVID-19 Task Force was adopted. The protocol included classifying patients based on clinical signs and symptoms and qPCR Cycle Threshold (CT) values, treating with a cocktail that included chloroquine or hydroxychloroquine, zinc, vitamins C and D and or antibiotic(s) as indicated. Physiotherapy and nutritional support for these patients were also considered as priority.
Results: During the period of study, 3,119 individuals tested for SARS-CoV-2 infection in Oyo State received a positive result and 310 (9.9%) were admitted to the IDC, Olodo, Ibadan. The average duration of admission was 10.22 ± 3.48 days, with 22(7.1%) patients requiring respiratory support by way of supplemental oxygen using re-breather bags and Continuous Positive Airway Pressure (CPAP)was used on one patient. No mortality was recorded among the 310 patients managed according to the protocol at the IDC,Olodo, Ibadan during the study period.
Conclusion: This clinical outcome suggests that the management protocol used in our center is effective and thus deserves evaluation for use in resource poor settings
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MALDI-ToF Analysis of Mitochondrial Peptides
MALDI-ToF Analysis of Mitochondrial Peptides
Adam Good, Alicia Wells, Ben Katz, Michael Alexander, Dmytro Klokol, Mike K.S. Chen,...
Abstract: Short peptides are known to play an important role in modulating transcription, in transmitting biological information and in restoring the genetic alterations that occur with aging. This paper aims to describe a method of identifying the population of peptides within a peptide cocktail formulation. A sample of lung-derived Mito Organelle (MO) Peptides (LBS) of specific pathogen free (SPF) mammalian rabbits sourced from Charles River Labs were analyzed by mass spectrometry and chromatograms were generated for further examination. The experimentally derived peaks were compared between two batches of LBS MO peptides using MALDI-ToF mass spectroscopy. The following report outlines the experimental methods and the results from performing MALDI-ToF mass spectrometry on various peptides from the company European Wellness (EW).
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Prevalence and Determinants of Retinopathy among Patients with Diabetes Mellitus: Thiqar 2022
Prevalence and Determinants of Retinopathy among Patients with Diabetes Mellitus: Thiqar 2022
Wajida Saa'd Bunyan, Ali Abed Saadoon, Muslim Nahi Saeed, Zahraa Jumaa Flayh, Hussain Ameer...
Background: Retinopathy among patients with type 2 diabetes appears to be a public health problem in Iraq; it is serious eye disease lead to sever visual impairment and blindness if not detected early.
Objective: To estimate the prevalence of retinopathy among patients with type 2 diabetes mellitus who attended National Center of Diabetes of Thi_qar and to determine the risk factors of diabetic retinopathy.
Methods: This cross-sectional study was conducted at national center of diabetes of Thi_qar between April and may 2022. 162 type 2 Iraqi diabetic patients both sexes were included in this study. Diabetic Retinopathy was diagnosed by an ophthalmologist depending on the International Clinical Diabetic Retinopathy Severity Scale approved by AAO and I CO. Socio-demographic, clinical and laboratory data were obtained from patients themselves, these variables include Sociodemographic, (sex and age), the participants residence, clinical data include, smoking, Hypertension or if the patient is currently using prescribed antihypertensive drugs, if have retinopathy and nephropathy, height and weight are measured.
Result: From 492 patients with diabetes mellitus, 272 patients (55.2%) had retinopathy (48 males, 42 females). The mean±SD of the age was 53.85 years. More than two third of patients were above 48 years old. 54.4% were hypertensive,26.6% cigarette smokers and 2.22% electronic hooka
Conclusion: This study showed high prevalence of diabetic retinopathy among type 2 diabetic patients, with poor control of blood glucose, high triglyceride, longer diabetes duration, hypertension, insulin treatment and age and gender as factor to develop retinopathy.
Keywords: Ritinopathy, DM, Thiqar ,2022
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Charecteristics of Pressure Sore of Spinal Cord Injury Patients Attentded at Crp
Charecteristics of Pressure Sore of Spinal Cord Injury Patients Attentded at Crp
Md. Mahbub Hossain, Most.Rabia Khatun, Umme Habiba
Purpose: The purpose of the study is to identify the Characteristics of pressure sore of spinal cord injury patients attended at CRP.
Objectives: To evaluate the characteristics of pressure sore among spinal cord injury patient attended at CRP.
Methodology: Method of the study was a cross sectional type of descriptive study which was conducted through face to face interviews, by using questionnaire with informed consent of the participants. Data were numerically coded and used in Excel and SPSS 20 version software program.
Result: Most of the participants had pressure sore 43% (n=13) participants were buttocks, 17 %( n=5) participants had pressure sore in coccyx region, 26% (n=8) participants had pressure sore in sacral region and 13 %( n=4) participants had pressure sore in leg. Among 30 participants, According to the degree of pressure sore, 13% (n=4) participants had one degree of pressure sore, 30% (n=9) participants had two degree of pressure sore, 40% (n=12) participants had three degree of pressure sore and 17% (n=5) participants had four degree of pressure sore.
Conclusion: Pressure sore is a serious complicated among SCI patients for which a lot of patients are dying every year. We must prevent pressure sore in order to improve rehab serious of SCI at institutional setting. Hospitals admit neurological impaired patients including SCI must administered appropriate measure to prevent ulcer.
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